FBXO6 antibody

FBXO6 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

FBXO6 Rabbit Polyclonal antibody. Positive WB detected in mouse liver tissue, Transfected HEK-293 cells. Positive IHC detected in human gliomas tissue. Observed molecular weight by Western-blot: 35 kDa

ELISA, IHC, WB

Human,Mouse,Rat; other species not tested.

F box only protein 6 antibody; F box protein 6 antibody; F box/G domain protein 2 antibody; FBG2 antibody; FBS2 antibody; FBX6 antibody; Fbx6b antibody; FBXO6 antibody

Rabbit IgG

This antibody was obtained by immunization of FBXO6 recombinant protein (Accession Number: NM_018438). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

FBXO6(F-box only protein 6 ) is also named as FBG2, FBS2, FBX6 and belongs to the F-box protein family. It can regulate Chk1 ubiquitination and degradation in both normally cycling cells and during replication stress. This protein is mainly detected in the cytoplasm in both cultured cells and in tumor tissues. Its expression is a predictive biomarker of tumor responsiveness to the important anticancer drugs.(PMID:19716789). FBXO6 can inhibit the anaphase promoting complex (cyclosome APC) and prevent mitotic exit in cytostatic factor (CSF) arrested eggs as a mitotic regulator.