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Product Name
FBXO41 antibody
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Description
FBXO41 Rabbit Polyclonal antibody. Positive IHC detected in human heart tissue, human brain tissue. Positive WB detected in mouse brain tissue, rat brain tissue. Positive IP detected in mouse brain tissue. Observed molecular weight by Western-blot: 100 kDa
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Tested applications
ELISA, WB, IP, IHC
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Species reactivity
Human, Mouse, Rat; other species not tested.
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Alternative names
F box only protein 41 antibody; F box protein 41 antibody; Fbx41 antibody; FBXO41 antibody; FLJ37709 antibody; KIAA1940 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of FBXO41 recombinant protein (Accession Number: BC112202). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IP: 1:500-1:5000
IHC: 1:20-1:200
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Validations
mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:110554(FBXO41 Antibody) at dilution of 1:1500
IP Result of anti-FBXO41 (IP:Catalog No:110554, 4ug; Detection:Catalog No:110554 1:1000) with mouse brain tissue lysate 6000ug.
Immunohistochemistry of paraffin-embedded human brain tissue slide using Catalog No:110554(FBXO41 Antibody) at dilution of 1:50 (under 40x lens)
Immunohistochemistry of paraffin-embedded human heart tissue slide using Catalog No:110554(FBXO41 Antibody) at dilution of 1:50 (under 40x lens)
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Background
FBXO41 also named as F box only protein 41 is a 875 amino-acid protein, which directly interact with SKP1 and CUL1. FBXO41 is identified as a Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex, which as a regulator mediates some protein ubiquitination degradation. FBXO41 consists of F-box domain and has zinc ion binding activity. FBXO41 may have an association with Parkinson’s disease.
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