FANCA-Specific antibody

FANCA-Specific antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

FANCA-Specific Rabbit Polyclonal antibody. Positive WB detected in HEK-293 cells, HeLa cells. Observed molecular weight by Western-blot: 163kd

ELISA, WB

Human; other species not tested.

Rabbit IgG

This antibody was obtained by immunization of Peptide (Accession Number: NM_000135). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

FANCA, also named as FAA, FACA and FANCH, is DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. FANCA may be involved in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Defects in FANCA are a cause of Fanconi anemia (FA) which is a genetically heterogeneous, autosomal recessive disorder characterized by progressive pancytopenia, a diverse assortment of congenital malformations, and a predisposition to the development of malignancies. The antibody is specific to isoform1 of FANCA.