FAM107A antibody

Cat.#: 110458

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Product Information

  • Product Name
    FAM107A antibody
  • Documents
  • Description
    FAM107A Rabbit Polyclonal antibody. Positive WB detected in Transfected HEK-293 cells. Positive IHC detected in human lung cancer tissue. Positive IF detected in MCF-7 cells.
  • Tested applications
    ELISA, IHC, IF, WB
  • Species reactivity
    Human, Mouse; other species not tested.
  • Alternative names
    DRR1 antibody; FAM107A antibody; FLJ30158 antibody; FLJ45473 antibody; Protein FAM107A antibody; Protein TU3A antibody; TU3A antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of FAM107A recombinant protein (Accession Number: NM_001076778). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IHC: 1:20-1:200

    IF: 1:10-1:100

  • Validations

    Immunohistochemical of paraffin-embedded human lung cancer using Catalog No:110458(FAM107A antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemical of paraffin-embedded human lung cancer using Catalog No:110458(FAM107A antibody) at dilution of 1:50 (under 10x lens)

    Immunofluorescent analysis of MCF-7 cells, using FAM107A antibody Catalog No:110458 at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

    Immunofluorescent analysis of MCF-7 cells, using FAM107A antibody Catalog No:110458 at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

    Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:110458(FAM107A Antibody) at dilution of 1:1000

    Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:110458(FAM107A Antibody) at dilution of 1:1000

  • Background
    FAM107A, also named as TU3A, encodes a 144 amino-acid protein, which contains a coiled-coil domain and a nuclear localization signal. FAM107A as a transcription factor regulates some gene transcription and signal transduction in cell. With the exception of peripheral blood cells, FAM107A is widely expressed in normal tissues, but shows significant loss of expression in renal cell carcinomas and frequent loss of expression in cervical, gastric, ovarian and non small cell lung cancers. Transfection of FAM107A mRNA into cancer cell line inhibits cell growth and proliferation, supporting the evidence that the gene functions as an important tumor suppressor.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"