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Product Name
Human EIF3K (His & GST Tag) recombinant protein
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Description
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
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Protein name
Eukaryotic translation initiation factor 3 subunit K
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Protein short names
EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT K; ARG134; EIF3K; M9; MSTP001; PLAC24; EUKARYOTIC TRANSLATION INITIATION FACTOR 3; SUBUNIT K; SUBUNIT 12; EIF-3 P25; PLAC-24; EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 12; EIF-3 P28; PRO1474; 1200009C21RIK; EIF3-P28; MUSCLE SPECIFIC; HSPC029; PTD001; MUSCLE-SPECIFIC GENE M9 PROTEIN; EIF3S12
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Uniprot ID
Q9UBQ5
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Gene Name
EIF3K; EIF3S12; ARG134; HSPC029; MSTP001; PTD001
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Source/Expression Host
Baculovirus-Insect Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human EIF3K (Q9UBQ5) (Ala2-Gln218) was expressed the N-terminal polyhistidine-tagged GST tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The secreted recombinant human EIF3K consists of 454 amino acids and predicts a molecular mass of 52.8 KDa. The apparent molecular mass of the protein is approximately 47 Kda in SDS-PAGE under reducing conditions due to glycosylation.
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Purity
> 90 % as determined by SDS-PAGE
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Validations
Human EIF3K Protein (His & GST Tag) SDS-PAGE
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