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Product Name
ETV5 antibody
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Description
ETV5 Rabbit Polyclonal antibody. Positive WB detected in PC-3 cells. Observed molecular weight by Western-blot: 58kd
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Tested applications
ELISA, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
ERM antibody; Ets related protein ERM antibody; ETS translOCation variant 5 antibody; ets variant 5 antibody; ETV5 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of ETV5 recombinant protein (Accession Number: NM_004454). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
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Validations
PC-3 cells were subjected to SDS PAGE followed by western blot with Catalog No:110489(ETV5 antibody) at dilution of 1:500
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Background
ETS variant gene 5(ETV5) belongs to the ETS oncogene family that shares a conserved peptide, ETS domain, which mediates sequence-specific DNA binding. ETV5 is a transcription factor and is required for spermatogonial stem cell self-renewal. ETV5 can be negatively regulated by COP1, a tumor suppressor. Also it has a role in branching morphogenesis in the developing kidney
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