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Product Name
ETV4 antibody
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Description
ETV4 Rabbit Polyclonal antibody. Positive WB detected in mouse heart tissue. Positive IHC detected in human ovary tumor tissue. Observed molecular weight by Western-blot: 61 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
E1A F antibody; E1AF antibody; ETS translOCation variant 4 antibody; ets variant 4 antibody; ETV4 antibody; PEA3 antibody; PEAS3 antibody; Protein PEA3 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of ETV4 recombinant protein (Accession Number: BC007242). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
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Validations
mouse heart tissue were subjected to SDS PAGE followed by western blot with Catalog No:110488(ETV4 antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human ovary tumor using Catalog No:110488(ETV4 antibody) at dilution of 1:50 (under 40x lens)
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Background
ETS translocation variant 4 (ETV4), also named as E1A-F or PEA3, is 484 amino acid protein, which contains one ETS DNA-binding domain and belongs to the ETS family. The calculated molecular weight of ETV4 protein is 54 kDa, but the phosphorylated ETV4 is a 54-61 kDa protein. ETV4 as a transcription activator localizes in the nucleus and binds to the enhancer of the adenovirus E1A gene.
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References
- Lee Y, Fryer JD, Kang H. ATXN1 protein family and CIC regulate extracellular matrix remodeling and lung alveolarization. Developmental cell. 21(4):746-57. 2011.
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