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Product Name
ERAB antibody
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Description
ERAB Mouse Monoclonal antibody. Positive WB detected in 293 cells, HEK-293 cells, human brain tissue, human liver tissue. Observed molecular weight by Western-blot: 27kd
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Tested applications
ELISA, WB
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
17 beta HSD 10 antibody; 17b HSD10 antibody; ABAD antibody; CAMR antibody; DUPXp11.22 antibody; ERAB antibody; HADH2 antibody; HCD2 antibody; HSD17B10 antibody; MHBD antibody; MRPP2 antibody; MRX17 antibody; MRX31 antibody; MRXS10 antibody; SCHAD antibody; SDR5C1 antibody; Type II HADH antibody; XH98G2 antibody
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Isotype
Mouse IgG1
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Preparation
This antibody was obtained by immunization of ERAB recombinant protein (Accession Number: NM_001037811). Purification method: Caprylic acid/ammonium sulfate precipitation.
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Clonality
Monoclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
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Validations
HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:107192(HSD17B10 antibody) at dilution of 1:1000
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Background
HSD17B10 (3-hydroxyacyl-CoA dehydrogenase type-2) is a multifunctional mitochondrial enzyme that acts on a wide spectrum of substrates, including neuroactive steroids, alcohols, leucine, and fatty acids, with a preference for short-chain methyl-branched acyl-CoAs(PMID:15860413).It has 2 isoforms produced by alternative splicing.Defects in HSD17B10 are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD deficiency) and mental retardation syndromic X-linked type 10 (MRXS10).
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