EIF4H antibody

EIF4H antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

EIF4H Rabbit Polyclonal antibody. Positive WB detected in HeLa cells, PC-3 cells. Observed molecular weight by Western-blot: 27kd

ELISA, WB

human, mouse, rat; other species not tested.

EIF4H antibody; WSCR1 antibody; KIAA0038 antibody; eIF 4H antibody; WBSCR1 antibody

Rabbit IgG

This antibody was obtained by immunization of EIF4H recombinant protein (Accession Number: NM_031992). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

eukaryotic initiation factor (eIF)4H, which encoded by the gene for HUMORFU_1, functions to stimulate the initiation of protein synthesis at the level of mRNA utilization. And its homolog in human, WBSCR1, located on 7q11, is commonly missed in patients suffered the Williams-Beuren syndrome, which is a complex neurodevelopmental disorder characterized by cardiovascular defects, cerebral dysplasias and a peculiar cognitive-behavioral profile. EIF4H has two kind of isoforms. The short isoform(~25kDa) is the predominant isoform and is expressed alone in liver and skeletal muscle. This is a rabbit anti-EIF4H polyclonal antibody raised against part of N-terminal chain of human EIF4H, and can recognize two kinds of isoform.

• Sarma N, Agarwal D, Shiflett LA, Read GS. Small interfering RNAs that deplete the cellular translation factor eIF4H impede mRNA degradation by the virion host shutoff protein of herpes simplex virus. Journal of virology. 82(13):6600-9. 2008.