EIF3G antibody

EIF3G antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

EIF3G Rabbit Polyclonal antibody. Positive IHC detected in human prostate cancer tissue. Positive IF detected in HepG2 cells, A549 cells. Positive WB detected in HepG2 cells. Observed molecular weight by Western-blot: 44kd

ELISA, WB, IHC, IF

Human,Mouse,Rat; other species not tested.

eIF 3 delta antibody; eIF 3 RNA binding subunit antibody; eIF3 delta antibody; EIF3 P42 antibody; eIF3 p44 antibody; EIF3G antibody; EIF3S4 antibody

Rabbit IgG

This antibody was obtained by immunization of EIF3G recombinant protein (Accession Number: NM_003755). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

Eukaryotic translation initiation factor eIF3, that plays a central role in translation initiation, consists of five core subunits that are present in both the budding yeast and higher eukaryotes. The EIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex. The complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. It is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. EIF3G is a component of the EIF3 complex. [PMID:20679478,20503360]