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Product Name
EGFL7 antibody
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Description
EGFL7 Rabbit Polyclonal antibody. Positive WB detected in human heart tissue. Positive IHC detected in human kidney tissue, human breast cancer tissue, human endometrial cancer tissue, human ovary tumor tissue. Observed molecular weight by Western-blot: 41-45 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
EGF like domain antibody; multiple 7 antibody; EGF like protein 7 antibody; EGFL7 antibody; MEGF7 antibody; NOTCH4 like protein antibody; RP11 251M1.2 antibody; Vascular endothelial statin antibody; VE STATIN antibody; ZNEU1 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of EGFL7 recombinant protein (Accession Number: XM_011518765). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
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Validations
human heart tissue were subjected to SDS PAGE followed by western blot with Catalog No:110215(EGFL7 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human kidney tissue slide using Catalog No:110215(EGFL7 Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human kidney tissue slide using Catalog No:110215(EGFL7 Antibody) at dilution of 1:50 (under 40x lens)
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Background
Epidermal growth factor-like domain-containing protein 7 (EGFL7), also known as vascular endothelial statin, is an endothelial cell-derived secreted factor that regulates vascular tube formation. This protein may be involved in the growth and proliferation of tumor cells. Recent studies have reported elevated expression of EGFL7 in several tumors and cancer cell lines, including kidney tumors, malignant gliomas, hepatocellular carcinomas, and colon cancers.
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References
- Wang XH, Huang WM. Astragalus polysaccharides exert protective effects in newborn rats with bronchopulmonary dysplasia by upregulating the expression of EGFL7 in lung tissue. International journal of molecular medicine. 34(6):1529-36. 2014.
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