EEF1E1 antibody

EEF1E1 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

EEF1E1 Rabbit Polyclonal antibody. Positive IHC detected in human breast cancer tissue. Positive WB detected in HepG2 cells, HEK-293 cells, human testis tissue, Jurkat cells, SKOV-3 cells. Observed molecular weight by Western-blot: 20kd

ELISA, IHC, WB

Human,Mouse,Rat; other species not tested.

AIMP3 antibody; EEF1E1 antibody; Elongation factor p18 antibody; P18 antibody

Rabbit IgG

This antibody was obtained by immunization of EEF1E1 recombinant protein (Accession Number: NM_004280). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

During the translation processes, aminoacyl-tRNA synthetases (ARSs) ligate specific amino acids to tRNAs. Together with non-enzymatic proteins called ARS-interacting multifunctional proteins (AIMPs), the ARSs form a macromolecular complex [PMID:15286174]. This complex has an essential role in protein synthesis, but also in other biological processes including angiogenesis, apoptosis and inflammation. [PMID:21789020] AIMP3 is not only associated with the multi-tRNA synthetase complex via its specific interaction with methionyl-tRNA synthetase, but also works as a tumor suppressor by interacting with ATM, the upstream kinase of p53 [PMID:18343821].