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Product Name
EDRF1 antibody
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Description
EDRF1 Rabbit Polyclonal antibody. Positive IHC detected in human testis tissue, human placenta tissue. Positive WB detected in PC-3 cells, HEK-293 cells, HeLa cells, human brain tissue, MCF7 cells, mouse brain tissue. Observed molecular weight by Western-blot: 140-160kd
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
C10orf137 antibody; EDRF1 antibody; RP11 383C5.6 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of EDRF1 recombinant protein (Accession Number: NM_001202438). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
PC-3 cells were subjected to SDS PAGE followed by western blot with Catalog No:110307(C10orf137 antibody) at dilution of 1:1000
Immunohistochemical of paraffin-embedded human testis using Catalog No:110307(C10orf137 antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemical of paraffin-embedded human testis using Catalog No:110307(C10orf137 antibody) at dilution of 1:50 (under 40x lens)
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Background
EDRF1, also named as C10orf137, is a transcription factor involved in erythroid differentiation. It regulates alpha- and gamma-globin gene synthesis by modulating DNA-binding activity of GATA-1 transcription factor. EDRF1 has four isoforms with MW 66 kDa, 89 kDa and 135-140 kDa.
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