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Product Name
EDG7-Specific antibody
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Description
EDG7-Specific Rabbit Polyclonal antibody. Positive WB detected in PC-3 cells, human testis tissue, mouse pancreas tissue. Positive IHC detected in human heart tissue. Positive FC detected in PC-3 cells. Observed molecular weight by Western-blot: 40-50 kDa
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Tested applications
ELISA, WB, IHC, FC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
Edg 7 antibody; EDG7 antibody; FLJ98231 antibody; GPCR antibody; HOFNH30 antibody; LP A3 antibody; LPA 3 antibody; LPA receptor 3 antibody; LPA3 antibody; LPAR3 antibody; RP4 678I3 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_012152). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
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Validations
PC-3 cells were subjected to SDS PAGE followed by western blot with Catalog No:110304(LPAR3-Specific antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human heart tissue slide using Catalog No:110304(LPAR3-Specific Antibody) at dilution of 1:100 (under 10x lens)
Immunohistochemistry of paraffin-embedded human heart tissue slide using Catalog No:110304(LPAR3-Specific Antibody) at dilution of 1:100 (under 40x lens)
1X10^6 PC-3 cells were stained with 0.2ug LPAR3-Specific antibody (Catalog No:110304, red) and control antibody (blue). Fixed with 4% PFA blocked with 3% BSA (30 min). Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) with dilution 1:1500.
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Background
LPAR3, also named as EDG7 and LPA3, belongs to the G-protein coupled receptor 1 family. LPAR3 is a receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. LPAR3 may play a role in the development of ovarian cancer. Seems to be coupled to the G(i)/G(o) and G(q) families of heteromeric G proteins. The antibody is specific to LPAR3.
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