Dymeclin antibody

Dymeclin antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Dymeclin Rabbit Polyclonal antibody. Positive WB detected in HEK-293 cells. Observed molecular weight by Western-blot: 76-80kd

ELISA, WB

Human,Mouse,Rat; other species not tested.

DMC antibody; DYM antibody; Dymeclin antibody; FLJ20071 antibody; FLJ90130 antibody; SMC antibody

Rabbit IgG

This antibody was obtained by immunization of Dymeclin recombinant protein (Accession Number: BC001252). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

Human Dymeclin is encoded by DYM gene, defects in which are the cause of Dyggve-Melchior-Clausen syndrome (DMC) and Smith-McCort dysplasia (SMC). DMC is a rare autosomal recessive disorder characterized by short trunk dwarfism, microcephaly and psychomotor retardation, with cutaneous cells containing dilated rough endoplasmic reticulum, enlarged and aberrant vacuoles and numerous vesicles [PubMed: 12491225]. Distinct with features of DMS, SMC is a rare osteochondrodysplasia characterized by short limbs and trunk with barrel-shaped chest [PubMed: 19005420]. Dymeclin is a not a stably anchored transmembrane protein with a transmembrane domain, but it shuttles between Golgi and cytosol, which is necessary for correct organization of Golgi apparatus [PubMed: 18996921].