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Product Name
DRD2 antibody
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Description
DRD2 Rabbit Polyclonal antibody. Positive IP detected in SH-SY5Y cells. Positive WB detected in SH-SY5Y cells, mouse brain tissue. Observed molecular weight by Western-blot: 47-55 kDa
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Tested applications
ELISA, WB, IP
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
D(2) dopamine receptor antibody; D2DR antibody; D2R antibody; Dopamine D2 receptor antibody; dopamine receptor D2 antibody; DRD2 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_016574). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IP: 1:200-1:1000
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Validations
SH-SY5Y cells were subjected to SDS PAGE followed by western blot with Catalog No:110016(DRD2 antibody) at dilution of 1:200
IP Result of anti-DRD2 (IP:Catalog No:110016, 4ug; Detection:Catalog No:110016 1:300) with SH-SY5Y cells lysate 3000ug.
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Background
DRD2, also named as D2DR and D2R, belongs to the G-protein coupled receptor 1 family. It is one of the five types (D1 to D5) of receptors for dopamine. The activity of DRD2 is mediated by G proteins which inhibit adenylyl cyclase. Defects in DRD2 are associated with dystonia type 11 (DYT11). The antibody is specific to DRD2.
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References
- Yan Y, Jiang W, Liu L. Dopamine controls systemic inflammation through inhibition of NLRP3 inflammasome. Cell. 160(1-2):62-73. 2015.
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