-
Product Name
DNAJC11 antibody
- Documents
-
Description
DNAJC11 Rabbit Polyclonal antibody. Positive WB detected in HeLa cells, mouse liver tissue, SH-SY5Y cells. Positive IHC detected in human skeletal muscle tissue, mouse brain tissue. Observed molecular weight by Western-blot: 63kd
-
Tested applications
ELISA, WB, IHC
-
Species reactivity
Human,Mouse,Rat; other species not tested.
-
Alternative names
dJ126A5.1 antibody; DNAJC11 antibody; FLJ10737 antibody
-
Isotype
Rabbit IgG
-
Preparation
This antibody was obtained by immunization of DNAJC11 recombinant protein (Accession Number: BC014145). Purification method: Antigen affinity purified.
-
Clonality
Polyclonal
-
Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
-
Storage instructions
Store at -20℃. DO NOT ALIQUOT
-
Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
-
Validations
HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:110103(DNAJC11 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human skeletal muscle tissue slide using Catalog No:110103(DNAJC11 Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human skeletal muscle tissue slide using Catalog No:110103(DNAJC11 Antibody) at dilution of 1:50 (under 40x lens)
-
Background
DNAJC11 is a member of the J proteins also known as HSP40 family of co-chaperones. Recently DNAJC11 has been found to interact with mitofilin, a mitochondrial inner membrane protein, indicating that it may be a molecular chaperone during mitochondrial protein import and folding.
-
References
- Ioakeimidis F, Ott C, Kozjak-Pavlovic V. A splicing mutation in the novel mitochondrial protein DNAJC11 causes motor neuron pathology associated with cristae disorganization, and lymphoid abnormalities in mice. PloS one. 9(8):e104237. 2014.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"