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Product Name
DLL4 antibody
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Description
DLL4 Rabbit Polyclonal antibody. Positive IP detected in mouse brain tissue. Positive WB detected in mouse brain tissue, A431 cells, Transfected HEK-293 cells. Observed molecular weight by Western-blot: 75-80 kDa
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Tested applications
ELISA, WB, IP
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
delta like 4 (Drosophila) antibody; Delta like protein 4 antibody; Delta4 antibody; DLL4 antibody; Drosophila Delta homolog 4 antibody; hdelta2 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of DLL4 recombinant protein (Accession Number: NM_019074). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:1000
IP: 1:200-1:1000
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Validations
mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:109997(DLL4 antibody) at dilution of 1:300
Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:109997(DLL4 Antibody) at dilution of 1:1000
IP Result of anti-DLL4 (IP:Catalog No:109997, 4ug; Detection:Catalog No:109997 1:300) with mouse brain tissue lysate 2800ug.
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Background
DLL4, also named as Delta4, plays a role in the Notch signaling pathway. It activates Notch-1 and Notch-4. Notch signaling is activated upon engagement of the Notch receptor with its ligands, the DSL (Delta, Serrate, Lag2) proteins of single-pass type I membrane proteins. DLL4 is highly expressed in the vascular endothelium.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"