DDX5,p68 antibody

DDX5,p68 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

DDX5,p68 Rabbit Polyclonal antibody. Positive IHC detected in human breast cancer tissue. Positive WB detected in NIH/3T3 cells, A431 cells, HeLa cells. Observed molecular weight by Western-blot: 65-68kd

ELISA, WB, IHC

Human,Mouse,Rat; other species not tested.

DDX5 antibody; DEAD box protein 5 antibody; DKFZp434E109 antibody; DKFZp686J01190 antibody; G17P1 antibody; HELR antibody; HLR1 antibody; HUMP68 antibody; p68 antibody; RNA helicase p68 antibody

Rabbit IgG

This antibody was obtained by immunization of DDX5,p68 recombinant protein (Accession Number: NM_001320596). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

DDX5 or p68, a member of DEAD/H BOX, which has a characterastic DEAD box, is a proliferation-associated nuclear antigen. DDX5 involves in the alternative regulation of pre-mRNA splicing, act as a RNA helicase to increase tau exon10 inclusion in a RBM4-dependent manner. It's also a transcription coactivator for extrogen receptor ESR1 and androgen receptor AR. Once synergized with DDX17 and SRA1 RNA, DDX5 activated MYOD1 transcription activity and involved in skeletal muscle differentiation. For the reason that DDX5 can be phosphorylated and dephosphorylated at several sites, at some cases the molecular weight of DDX5 is less than 68kD, approximately 65kd