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Product Name
DCP1A antibody
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Description
DCP1A Rabbit Polyclonal antibody. Positive WB detected in mouse lung tissue, Jurkat cells, mouse brain tissue. Positive IP detected in mouse brain tissue. Positive IHC detected in mouse lung tissue. Observed molecular weight by Western-blot: 70 kDa
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Tested applications
ELISA, WB, IHC, IP
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
DCP1A antibody; FLJ21691 antibody; HSA275986 antibody; mRNA decapping enzyme 1A antibody; Nbla00360 antibody; SMAD4IP1 antibody; SMIF antibody; Transcription factor SMIF antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of DCP1A recombinant protein (Accession Number: NM_018403). Purification method: Antigen Affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IP: 1:1000-1:10000
IHC: 1:20-1:200
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Validations
mouse lung tissue were subjected to SDS PAGE followed by western blot with Catalog No:109754(DCP1A antibody) at dilution of 1:1000
IP Result of anti-DCP1A (IP:Catalog No:109754, 4ug; Detection:Catalog No:109754 1:3000) with mouse brain tissue lysate 3200ug.
Immunohistochemistry of paraffin-embedded mouse lung tissue slide using Catalog No:109754(DCP1A Antibody) at dilution of 1:50 (under 40x lens)
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Background
DCP1 decapping enzyme homolog A (S. cerevisiae), known as mRNA-decapping enzyme 1A (DCP1A),is necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Contributes to the transactivation of target genes after stimulation by TGFB1. This antibody specifically react with the 70kd DCP1A protein.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"