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Product Name
CYP2D6 antibody
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Description
CYP2D6 Rabbit Polyclonal antibody. Positive IHC detected in human kidney tissue, human liver tissue. Positive WB detected in mouse liver tissue. Observed molecular weight by Western-blot: 50 kDa,65 kDa
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Tested applications
ELISA, IHC, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
CPD6 antibody; CYP2D antibody; CYP2D@ antibody; CYP2D6 antibody; CYP2DL1 antibody; CytOChrome P450 2D6 antibody; P450 DB1 antibody; P450C2D antibody; P450DB1 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of CYP2D6 recombinant protein (Accession Number: NM_000106). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:1000
IHC: 1:20-1:200
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Validations
mouse liver tissue were subjected to SDS PAGE followed by western blot with Catalog No:109693(CYP2D6 Antibody) at dilution of 1:300
Immunohistochemical of paraffin-embedded human kidney using Catalog No:109693(CYP2D6 antibody) at dilution of 1:50 (under 10x lens)
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Background
CYP2D6(Cytochrome P450 2D6) is also named as CYP2DL1 and belongs to the cytochrome P450 family. It is a monooxygenase that involved in the metabolism of drugs such as antiarrhythmics, adrenoceptor antagonists, and tricyclic antidepressants. CYP2D6 is responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It has 2 isoforms produced by alternative splicing with the molecular weight of 56 kDa and 50 kDa.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"