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Product Name
CTPS2 antibody
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Description
CTPS2 Rabbit Polyclonal antibody. Positive IHC detected in human prostate cancer tissue, human colon tissue. Positive WB detected in mouse testis tissue, human adrenal gland tissue. Observed molecular weight by Western-blot: 66 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
CTP synthase 2 antibody; CTP synthase II antibody; CTP synthetase 2 antibody; CTPS2 antibody; DKFZp686C17207 antibody; FLJ43358 antibody; UTP ammonia ligase 2 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of CTPS2 recombinant protein (Accession Number: NM_019857). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
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Validations
mouse testis tissue were subjected to SDS PAGE followed by western blot with Catalog No:109729(CTPS2 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human prostate cancer tissue slide using Catalog No:109729(CTPS2 Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human prostate cancer tissue slide using Catalog No:109729(CTPS2 Antibody) at dilution of 1:50 (under 40x lens)
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Background
CTPS2 (CTP synthase 2) is also named as UTP--ammonia ligase 2 and belongs to the CTP synthase family.It catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen and constitutes the rate-limiting enzyme in the synthesis of cytosine nucleotides.
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References
- Keppeke GD, Calise SJ, Chan EK, Andrade LE. Assembly of IMPDH2-based, CTPS-based, and mixed rod/ring structures is dependent on cell type and conditions of induction. Journal of genetics and genomics = Yi chuan xue bao. 42(6):287-99. 2015.
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