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CSNK2A2 antibody

Cat.#: 109604

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Product Information

  • Product Name
    CSNK2A2 antibody
  • Documents
  • Description
    CSNK2A2 Rabbit Polyclonal antibody. Positive IF detected in HepG2 cells. Positive IP detected in HEK-293 cells. Positive WB detected in HepG2 cells, HEK-293 cells, HT-1080 cells, Jurkat cells. Observed molecular weight by Western-blot: 30-35 kDa
  • Tested applications
    ELISA, WB, IP, IF
  • Species reactivity
    Human; other species not tested.
  • Alternative names
    Casein kinase II subunit alpha antibody; CK II alpha antibody; CK2A2 antibody; CSNK2A1 antibody; CSNK2A2 antibody; FLJ43934 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of CSNK2A2 recombinant protein (Accession Number: XM_047433626). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IP: 1:200-1:2000

    IF: 1:20-1:200

  • Validations

    HepG2 cells were subjected to SDS PAGE followed by western blot with Catalog No:109604(CSNK2A2 antibody) at dilution of 1:500

    HepG2 cells were subjected to SDS PAGE followed by western blot with Catalog No:109604(CSNK2A2 antibody) at dilution of 1:500

    IP Result of anti-CSNK2A2 (IP:Catalog No:109604, 4ug; Detection:Catalog No:109604 1:600) with HEK-293 cells lysate 2800ug.

    IP Result of anti-CSNK2A2 (IP:Catalog No:109604, 4ug; Detection:Catalog No:109604 1:600) with HEK-293 cells lysate 2800ug.

    Immunofluorescent analysis of HepG2 cells using Catalog No:109604(CSNK2A2 Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

    Immunofluorescent analysis of HepG2 cells using Catalog No:109604(CSNK2A2 Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

  • Background
    CSNK2A2(Casein kinase II subunit alpha') is also named as CK2A3, CK2A2, CSNK2A1, CK2 and belongs to the protein kinase superfamily. It can function as a component of the p53/TP53-dependent spindle assembly checkpoint (SAC) that maintains cyclin-B-CDK1 activity and G2 arrest in response to spindle damage during mitosis. It also can protect against ionizing radiation-induced apoptosis partly by phosphorylating and activating SIRT1. This protein has a molecular weight between 35 kDa and 44 kDa(PMID:8622692).

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"