-
Product Name
CRISP3 antibody
- Documents
-
Description
CRISP3 Rabbit Polyclonal antibody. Positive IP detected in human placenta tissue. Positive WB detected in human placenta tissue, Jurkat cells, mouse colon tissue, mouse ovary tissue, mouse thymus tissue. Positive IHC detected in human pancreas tissue, human colon cancer tissue, human prostate hyperplasia tissue. Observed molecular weight by Western-blot: 29 kDa
-
Tested applications
ELISA, WB, IHC, IP
-
Species reactivity
Human, Mouse; other species not tested.
-
Alternative names
Aeg2 antibody; CRISP 3 antibody; CRISP3 antibody; CRS3 antibody; dJ442L6.3 antibody; SGP28 antibody
-
Isotype
Rabbit IgG
-
Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_006061). Purification method: Antigen affinity purified.
-
Clonality
Polyclonal
-
Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
-
Storage instructions
Store at -20℃. DO NOT ALIQUOT
-
Applications
Recommended Dilution:
WB: 1:500-1:5000
IP: 1:200-1:1000
IHC: 1:20-1:200
-
Validations
human placenta tissue were subjected to SDS PAGE followed by western blot with Catalog No:109564(CRISP3 antibody) at dilution of 1:300
IP Result of anti-CRISP3 (IP:Catalog No:109564, 4ug; Detection:Catalog No:109564 1:300) with human placenta tissue lysate 1520ug.
Immunohistochemistry of paraffin-embedded human pancreas tissue slide using Catalog No:109564(CRISP3 Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human pancreas tissue slide using Catalog No:109564(CRISP3 Antibody) at dilution of 1:50 (under 40x lens)
-
Background
CRISP3, also known as SGP28, is a glycoprotein that belongs to a family of cysteine-rich secretory proteins (CRISPs). CRISP3 was originally discovered in human neutrophils, but transcripts are widely distributed in exocrine glands (salivary glands, pancreas, and prostate) and also found at lower levels in epididymis, ovary, thymus, and colon. CRISP3 is a potential biomarker for prostate cancer. This antibody can recgnize both CRISP2 and CRISP3.
-
References
- Al Bashir S, Alshalalfa M, Hegazy SA, Dolph M, Donnelly B, Bismar TA. Cysteine- rich secretory protein 3 (CRISP3), ERG and PTEN define a molecular subtype of prostate cancer with implication to patients' prognosis. Journal of hematology & oncology. 7:21. 2014.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"