CRIPT antibody

Cat.#: 109562

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Product Information

  • Product Name
    CRIPT antibody
  • Documents
  • Description
    CRIPT Rabbit Polyclonal antibody. Positive IF detected in L02 cells. Positive WB detected in L02 cells. Positive IP detected in L02 cells. Observed molecular weight by Western-blot: 15 kDa
  • Tested applications
    ELISA, WB, IP, IF
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    CRIPT antibody; HSPC139 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of CRIPT recombinant protein (Accession Number: NM_014171). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IP: 1:200-1:2000

    IF: 1:20-1:200

  • Validations

    L02 cells were subjected to SDS PAGE followed by western blot with Catalog No:109562(CRIPT antibody) at dilution of 1:500

    L02 cells were subjected to SDS PAGE followed by western blot with Catalog No:109562(CRIPT antibody) at dilution of 1:500

    IP Result of anti-CRIPT (IP:Catalog No:109562, 4ug; Detection:Catalog No:109562 1:500) with L02 cells lysate 1800ug.

    IP Result of anti-CRIPT (IP:Catalog No:109562, 4ug; Detection:Catalog No:109562 1:500) with L02 cells lysate 1800ug.

    Immunofluorescent analysis of L02 cells using Catalog No:109562(CRIPT Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

    Immunofluorescent analysis of L02 cells using Catalog No:109562(CRIPT Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

  • Background
    The clustering and immobilization of receptors and ion channels located at specific subcellular sites are believed to be mediated by intracellular proteins that attach these membrane proteins to the cytoskeleton. Receptors and ion channels interact with cytoplasmic proteins, which involved in the modulation or downstream signaling mechanisms of the receptor/ion channel. CRIPT is the protein that binds to the third PDZ (PDZ3) domain of PSD95, which binds to and clusters a variety of membrane proteins, including Shaker-type potassium channel subunits and NMDA receptor NR2 subunits, via its first 2 N-terminal PDZ domains

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"