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Product Name
COX6B2 antibody
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Description
COX6B2 Rabbit Polyclonal antibody. Positive WB detected in mouse heart tissue. Positive IHC detected in mouse testis tissue. Observed molecular weight by Western-blot: 11kd
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
Cancer/testis antigen 59 antibody; COX VIb 2 antibody; COX6B2 antibody; COXVIB2 antibody; CT59 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of COX6B2 recombinant protein (Accession Number: BC064548). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:1000
IHC: 1:20-1:200
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Validations
mouse heart tissue were subjected to SDS PAGE followed by western blot with Catalog No:109495(COX6B2 antibody) at dilution of 1:100
Immunohistochemistry of paraffin-embedded mouse testis tissue slide using Catalog No:109495(COX6B2 Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded mouse testis tissue slide using Catalog No:109495(COX6B2 Antibody) at dilution of 1:50 (under 40x lens)
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Background
COX6B2(Cytochrome c oxidase subunit 6B2) encodes the testis-specific cytochrome C oxidase subunit VIb. It has been shown to be expressed in a subset of lung and breast tumors at a level >1% of the testicular level of expression(PMID: 24491090). It belongs to the cytochrome c oxidase subunit 6B family.
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References
- Oliva CR, Nozell SE, Diers A. Acquisition of temozolomide chemoresistance in gliomas leads to remodeling of mitochondrial electron transport chain. The Journal of biological chemistry. 285(51):39759-67. 2010.
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