COX6A1 antibody

Cat.#: 109493

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Product Information

  • Product Name
    COX6A1 antibody
  • Documents
  • Description
    COX6A1 Rabbit Polyclonal antibody. Positive IHC detected in human pancreas cancer tissue. Positive WB detected in human brain tissue, NIH/3T3 cells. Observed molecular weight by Western-blot: 9.5 kDa
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    COX VIa L antibody; COX6A antibody; COX6A1 antibody; COX6AL antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of COX6A1 recombinant protein (Accession Number: NM_004373). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IHC: 1:20-1:200

  • Validations

    human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:109493(COX6A1 antibody) at dilution of 1:500

    human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:109493(COX6A1 antibody) at dilution of 1:500

    Immunohistochemical of paraffin-embedded human pancreas cancer using Catalog No:109493(COX6A1 antibody) at dilution of 1:100 (under 10x lens)

    Immunohistochemical of paraffin-embedded human pancreas cancer using Catalog No:109493(COX6A1 antibody) at dilution of 1:100 (under 10x lens)

  • Background
    COX6A1(Cytochrome c oxidase subunit 6A1, mitochondrial) is also named as COX6AL and belongs to the cytochrome c oxidase subunit 6A family.This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
  • References
    • Oliva CR, Nozell SE, Diers A. Acquisition of temozolomide chemoresistance in gliomas leads to remodeling of mitochondrial electron transport chain. The Journal of biological chemistry. 285(51):39759-67. 2010.
    • Huang R, Zhao L, Chen H. Megakaryocytic differentiation of K562 cells induced by PMA reduced the activity of respiratory chain complex IV. PloS one. 9(5):e96246. 2014.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"