COX-1/Cyclooxygenase-1 antibody

Cat.#: 109481

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Product Information

  • Product Name
    COX-1/Cyclooxygenase-1 antibody
  • Documents
  • Description
    COX-1/Cyclooxygenase-1 Rabbit Polyclonal antibody. Positive WB detected in mouse lung tissue, mouse kidney tissue. Positive IHC detected in human stomach tissue. Observed molecular weight by Western-blot: 72 kDa
  • Tested applications
    ELISA, IHC, WB
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    COX1 antibody; COX-1 antibody; COX3 antibody; Cyclooxygenase 1 antibody; PCOX1 antibody; PGG/HS antibody; PGH synthase 1 antibody; PGHS 1 antibody; PGHS1 antibody; PHS 1 antibody; PHS1 antibody; Prostaglandin G/H synthase 1 antibody; Prostaglandin H2 synthase 1 antibody; PTGHS antibody; PTGS1 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of COX-1/Cyclooxygenase-1 recombinant protein (Accession Number: NM_000962). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:1000

    IHC: 1:20-1:200

  • Validations

    mouse lung tissue were subjected to SDS PAGE followed by western blot with Catalog No:109481(PTGS1 antibody) at dilution of 1:200

    mouse lung tissue were subjected to SDS PAGE followed by western blot with Catalog No:109481(PTGS1 antibody) at dilution of 1:200

    Immunohistochemical of paraffin-embedded human stomach using Catalog No:109481(PTGS1 antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemical of paraffin-embedded human stomach using Catalog No:109481(PTGS1 antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemical of paraffin-embedded human stomach using Catalog No:109481(PTGS1 antibody) at dilution of 1:50 (under 40x lens)

    Immunohistochemical of paraffin-embedded human stomach using Catalog No:109481(PTGS1 antibody) at dilution of 1:50 (under 40x lens)

  • Background
    PTGS1(Prostaglandin G/H synthase 1) belongs to the prostaglandin G/H synthase family and catalyzes the conversion of arachidonic acid to prostaglandin H2, which is subsequently metabolized to various biologically active prostaglandins.It is also named as COX1(Cyclooxygenase-1).There is no PTGS1 expression in fetal samples (prostate, seminal vesicles, or ejaculatory ducts), and only minimal expression in adult tissues(PMID: 10999846).
  • References
    • Aras S, Bai M, Lee I, Springett R, Hüttemann M, Grossman LI. MNRR1 (formerly CHCHD2) is a bi-organellar regulator of mitochondrial metabolism. Mitochondrion. 20:43-51. 2015.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"