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Product Name
CORO1C antibody
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Description
CORO1C Rabbit Polyclonal antibody. Positive WB detected in mouse skeletal muscle tissue, human heart tissue. Positive IP detected in mouse skeletal muscle tissue. Positive IHC detected in human cervical cancer tissue. Positive IF detected in HepG2 cells. Observed molecular weight by Western-blot: 57kd
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Tested applications
ELISA, WB, IHC, IF, IP
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
CORO1C antibody; Coronin 1C antibody; Coronin 3 antibody; CRNN4 antibody; HCRNN4 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of CORO1C recombinant protein (Accession Number: XM_017019123). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IP: 1:200-1:2000
IHC: 1:20-1:200
IF: 1:10-1:100
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Validations
mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with Catalog No:109475(CORO1C antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human cervical cancer using Catalog No:109475(CORO1C antibody) at dilution of 1:100 (under 10x lens)
Immunohistochemical of paraffin-embedded human cervical cancer using Catalog No:109475(CORO1C antibody) at dilution of 1:100 (under 40x lens)
Immunofluorescent analysis of HepG2 cells, using CORO1C antibody Catalog No:109475 at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
IP Result of anti-CORO1C (IP:Catalog No:109475, 4ug; Detection:Catalog No:109475 1:500) with mouse skeletal muscle tissue lysate 3600ug.
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Background
CORO1C represents coronin, actin binding protein, 1C
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References
- Wu L, Peng CW, Hou JX. Coronin-1C is a novel biomarker for hepatocellular carcinoma invasive progression identified by proteomics analysis and clinical validation. Journal of experimental & clinical cancer research : CR. 29:17. 2010.
- Wang ZG, Jia MK, Cao H, Bian P, Fang XD. Knockdown of Coronin-1C disrupts Rac1 activation and impairs tumorigenic potential in hepatocellular carcinoma cells. Oncology reports. 29(3):1066-72. 2013.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"