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Product Name
COQ9 antibody
- Documents
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Description
COQ9 Rabbit Polyclonal antibody. Positive IF detected in HepG2 cells. Positive IHC detected in human cervical cancer tissue. Positive WB detected in human kidney tissue, HeLa cells, human liver tissue. Positive IP detected in HeLa cells. Observed molecular weight by Western-blot: 36kd
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Tested applications
ELISA, WB, IHC, IF, IP
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Species reactivity
Human, Rat; other species not tested.
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Alternative names
C16orf49 antibody; COQ9 antibody; DKFZp434K046 antibody; PSEC0129 antibody
- Immunogen
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of COQ9 recombinant protein (Accession Number: NM_020312). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IP: 1:200-1:2000
IHC: 1:20-1:200
IF: 1:10-1:100
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Validations
human kidney tissue were subjected to SDS PAGE followed by western blot with Catalog No:109473(COQ9 antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human cervical cancer using Catalog No:109473(COQ9 antibody) at dilution of 1:100 (under 40x lens)
Immunofluorescent analysis of HepG2 cells, using COQ9 antibody Catalog No:109473 at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
IP Result of anti-COQ9 (IP:Catalog No:109473, 3ug; Detection:Catalog No:109473 1:500) with HeLa cells lysate 1840ug.
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Background
COQ9, also named as C16orf49, HSPC326, and PSEC0129, is a 318 amino acid protein, which belongs to the COQ9 family. COQ9 localizes in the Mitochondrion and is involved in the biosynthesis of coenzyme Q COQ9 has abilities to improve left ventricular performance and to reduce myocardial infarct size and cardiomyocyte apoptosis.
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References
- Heeringa SF, Chernin G, Chaki M. COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness. The Journal of clinical investigation. 121(5):2013-24. 2011.
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