CLEC2D antibody

CLEC2D antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

CLEC2D Rabbit Polyclonal antibody. Positive WB detected in Jurkat cells. Observed molecular weight by Western-blot: 33 kDa

ELISA, WB

Human; other species not tested.

CLAX antibody; CLEC2D antibody; Lectin like NK cell receptor antibody; Lectin like transcript 1 antibody; LLT 1 antibody; LLT1 antibody; OCIL antibody; OsteOClast inhibitory lectin antibody

Rabbit IgG

This antibody was obtained by immunization of CLEC2D recombinant protein (Accession Number: BC019883). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

CLEC2D (C-type lectin domain family 2 member D), also known as LLT1 (lectin-like transcript 1) or ocIL (Osteoclast inhibitory lectin), is a single-pass type II membrane protein expressed by hematopoietic cells and osteoblasts (PMID: 21930700; 14753741). Its expression was found to be tightly correlated with activation on T cells, NK cells, B cells, and DCs (PMID: 21930700). CLEC2D is a ligand for the human NKR-P1A (CD161) receptor and that their interaction differentially regulates NK- and T-cell functions (PMID: 16339513, 16339512). It inhibits the formation and function of osteoclasts and modulates the release of interferon-gamma by human NK cells (PMID:14753741; 20415786).