Chromogranin A antibody

Cat.#: 107157

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Product Information

  • Product Name
    Chromogranin A antibody
  • Documents
  • Description
    Chromogranin A Mouse Monoclonal antibody. Positive WB detected in rat pancreas tissue, human adrenal gland tissue, Transfected HEK-293 cells. Positive IHC detected in human pancreas tissue, human colon tissue. Observed molecular weight by Western-blot: 70 kDa
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human, Rat; other species not tested.
  • Alternative names
    CGA antibody; CHGA antibody; Chromogranin A antibody; Pituitary secretory protein I antibody; SP I antibody; Vasostatin I Vasostatin 2 antibody
  • Isotype
    Mouse IgG1
  • Preparation
    This antibody was obtained by immunization of Chromogranin A recombinant protein (Accession Number: NM_001275). Purification method: Protein G purified.
  • Clonality
    Monoclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IHC: 1:50-1:500

  • Validations

    rat pancreas tissue were subjected to SDS PAGE followed by western blot with Catalog No:107157(CHGA antibody) at dilution of 1:1000

    rat pancreas tissue were subjected to SDS PAGE followed by western blot with Catalog No:107157(CHGA antibody) at dilution of 1:1000

    Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:107157(CHGA Antibody) at dilution of 1:500

    Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:107157(CHGA Antibody) at dilution of 1:500

    Immunohistochemistry of paraffin-embedded human pancreas tissue slide using Catalog No:107157(CHGA Antibody) at dilution of 1:200 (under 10x lens).

    Immunohistochemistry of paraffin-embedded human pancreas tissue slide using Catalog No:107157(CHGA Antibody) at dilution of 1:200 (under 10x lens).

    Immunohistochemistry of paraffin-embedded human pancreas tissue slide using Catalog No:107157(CHGA Antibody) at dilution of 1:200 (under 40x lens).

    Immunohistochemistry of paraffin-embedded human pancreas tissue slide using Catalog No:107157(CHGA Antibody) at dilution of 1:200 (under 40x lens).

  • Background
    Chromogranin A is a member of the granin family of neuroendocrine secretory proteins. It is located in secretory vesicles of neurons and endocrine cells. Chromogranin A is the precursor to several functional peptides including vasostatin, pancreastatin, catestatin and parastatin. These peptides negatively modulate the neuroendocrine function of the releasing cell (autocrine) or nearby cells (paracrine). CgA is one of the most used tumor markers in NET's (neuroendocrine tumors) , and elevated CgA concentrations have been demonstrated in serum or plasma of patients with different types of these tumors.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"