CHAD antibody

CHAD antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

CHAD Rabbit Polyclonal antibody. Positive WB detected in MCF7 cells, HeLa cells, Jurkat cells. Observed molecular weight by Western-blot: 41 kDa

ELISA, WB

Human,Mouse,Rat; other species not tested.

Cartilage leucine rich protein antibody; CHAD antibody; chondroadherin antibody; SLRR4A antibody

Rabbit IgG

This antibody was obtained by immunization of CHAD recombinant protein (Accession Number: NM_001267). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

Chondroadherin (CHAD), also known as cartilage leucine-rich protein, is a prominent noncollagenous extracellular protein in cartilage. It was first isolated from bovine cartilage. The primary structure of CHAD shows that it belongs to the family of leucine-rich repeat (LRR) proteins. It is expressed at high levels in certain zones of cartilage and also has been detected in bone, tendon, bone marrow, and chondrosarcoma cells. CHAD promotes attachment of chondrocytes, fibroblasts, and osteoblasts, mediated via the integrin alpha2beta1. It has also been shown to bind to collagen type II and both collagen type II and chondroadherin interact with integrin alpha2beta1. Besides, CHAD may play an important role in the regulation of chondrocyte growth and proliferation.