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Product Name
CEP350-Specific antibody
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Description
CEP350-Specific Rabbit Polyclonal antibody. Positive IHC detected in human testis tissue. Positive WB detected in mouse heart tissue, Y79 cells. Observed molecular weight by Western-blot: 200-245kd,143kd,65kd
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
CAP350 antibody; centrosomal protein 350kDa antibody; CEP350 antibody; FLJ38282 antibody; FLJ44058 antibody; GM133 antibody; KIAA0480 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_014810). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
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Validations
mouse heart tissue were subjected to SDS PAGE followed by western blot with Catalog No:109180(CEP350-Specific antibody) at dilution of 1:600
Immunohistochemistry of paraffin-embedded human testis slide using Catalog No:109180(CEP350-Specific Antibody) at dilution of 1:50
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Background
CEP350, also named as CAP350, FLJ38282, FLJ44058, GM133 and KIAA0480, plays an essential role in centriole growth by stabilizing a procentriolar seed composed of at least, SASS6 and CENPJ. It is required for anchoring microtubules to the centrosomes and for the integrity of the microtubule network. CEP350 recruits PPARA to discrete subcellular compartments and thereby modulates PPARA activity. The antibody is specific to CEP350.
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