CDX2 antibody

CDX2 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

CDX2 Mouse Monoclonal antibody. Positive WB detected in human brain tissue. Observed molecular weight by Western-blot: 33-40KD

ELISA, WB

Human,Mouse, Rat; other species not tested.

caudal type homeobox 2 antibody; Caudal type homeobox protein 2 antibody; CDX 3 antibody; CDX2 antibody; CDX3 antibody; Homeobox protein CDX 2 antibody

Mouse IgG1

This antibody was obtained by immunization of CDX2 recombinant protein (Accession Number: NM_001265). Purification method: Protein G purified.

Monoclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

CDX2, also named as Homeobox protein CDX-2, is a 313 amino acid protein, which contains one homeobox DNA-binding domain and belongs to the Caudal homeobox family. CDX2 localizes in the nucleus and is involved in the transcriptional regulation of multiple genes expression in the intestinal epithelium. The relative expression of CDX1 to CDX2 protein may be important in the anterior to posterior patterning of the intestinal epithelium and in defining patterns of proliferation and differentiation along the crypt-villus axis. Both Cdx1 and Cdx2 genes must be expressed to reduce tumorigenic potential, to increase sensitivity to apoptosis, and to reduce cell migration, suggesting that the two genes control the normal phenotype by independent pathways.