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Product Name
CDT1 antibody
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Description
CDT1 Rabbit Polyclonal antibody. Positive WB detected in Jurkat cells, HepG2 cells. Positive IF detected in HepG2 cells. Observed molecular weight by Western-blot: 65 kDa
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Tested applications
ELISA, WB, IF
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Species reactivity
Human; other species not tested.
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Alternative names
CDT1 antibody; DNA replication factor Cdt1 antibody; Double parked homolog antibody; DUP antibody; RIS2 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of CDT1 recombinant protein (Accession Number: NM_030928). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IF: 1:50-1:500
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Validations
Jurkat cells were subjected to SDS PAGE followed by western blot with Catalog No:109175(CDT1 antibody) at dilution of 1:500
Immunofluorescent analysis of (10% Formaldehyde) fixed HepG2 cells using Catalog No:109175(CDT1 Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Background
CDT1, also named as DUP, is an essential licensing protein for DNA replication, can function as an oncogene in mammals. CDT1 is a 60-65 kDa protein for phosphor modification.
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References
- Lin HK, Chen Z, Wang G. Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. Nature. 464(7287):374-9. 2010.
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