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Product Name
CDR2L antibody
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Description
CDR2L Rabbit Polyclonal antibody. Positive IF detected in HepG2 cells. Positive IP detected in SH-SY5Y cells. Positive WB detected in SH-SY5Y cells, K-562 cells. Observed molecular weight by Western-blot: 62 kDa
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Tested applications
ELISA, WB, IF, IP
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
CDR2L antibody; HUMPPA antibody; Paraneoplastic 62 kDa antigen antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of CDR2L recombinant protein (Accession Number: BC047534). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IP: 1:200-1:2000
IF: 1:20-1:200
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Validations
SH-SY5Y cells were subjected to SDS PAGE followed by western blot with Catalog No:109173(CDR2L antibody) at dilution of 1:500
IP Result of anti-CDR2L (IP:Catalog No:109173, 3ug; Detection:Catalog No:109173 1:500) with SH-SY5Y cells lysate 2500ug.
Immunofluorescent analysis of HepG2 cells using Catalog No:109173(CDR2L Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Background
Cerebellar degeneration-related protein 2-like(CDR2L), also named as HUMPPA or Paraneoplastic 62 kDa antigen, is a 465 amino acid protein, which belongs to the CDR2 family. CDR2L contains three potential coiled-coil regions. The functions of protein is so far not known. CDR2L is expressed in the brain and localizes in the cytoplasm.
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References
- Schubert M, Panja D, Haugen M, Bramham CR, Vedeler CA. Paraneoplastic CDR2 and CDR2L antibodies affect Purkinje cell calcium homeostasis. Acta neuropathologica. 128(6):835-52. 2014.
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