Human TRIP10/Protein Felic (His Tag)

Cat.#: 502498

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Product Information

  • Product Name
    Human TRIP10/Protein Felic (His Tag)
  • Documents
  • Description
    Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling (By similarity). Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL.
  • Protein name
    Cdc42-interacting protein 4
  • Protein short names
    AI646975; HSTP; CDC42-INTERACTING PROTEIN 4; THYROID HORMONE RECEPTOR INTERACTOR 10; STP; THYROID RECEPTOR INTERACTING PROTEIN 10; THYROID RECEPTOR-INTERACTING PROTEIN 10; TRIP-10; PROTEIN FELIC; SALT TOLERATOR; STOT; TRIP10; SALT TOLERANT PROTEIN; CIP4; TR-INTERACTING PROTEIN 10; CDC42 INTERACTING PROTEIN-4
  • Uniprot ID
    Q15642
  • Gene Name
    TRIP10; CIP4; STOT; STP
  • Source/Expression Host
    Baculovirus-Insect Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human TRIP10 Isoform 2 (NP_004231.1) (Met1-Asn545) was expressed with a C-terminal polyhistidine tag.
  • Protein Species
    Human
  • Molecular weight
    The secreted recombinant human TRIP10 consists of 556 amino acids and predicts a molecular mass of 64 KDa. The apparent molecular mass of the protein is approximately 84.2 KDa in SDS-PAGE under reducing conditions.
  • Purity
    > 85 % as determined by SDS-PAGE
  • Validations

    Human TRIP10 / Cip4 Protein (His Tag) SDS-PAGE

    Human TRIP10 / Cip4 Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"