CD47 antibody

Cat.#: 107138

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Product Information

  • Product Name
    CD47 antibody
  • Documents
  • Description
    CD47 Mouse Monoclonal antibody. Positive WB detected in SKOV-3 cells, HT-1080 cells, HUVEC cells. Observed molecular weight by Western-blot: 55 kDa
  • Tested applications
    ELISA, WB
  • Species reactivity
    Human; other species not tested.
  • Alternative names
    CD47 antibody; CD47 molecule antibody; IAP antibody; Integrin assOCiated protein antibody; LeukOCyte surface antigen CD47 antibody; MER6 antibody; OA3 antibody; Protein MER6 antibody
  • Isotype
    Mouse IgG2b
  • Preparation
    This antibody was obtained by immunization of CD47 recombinant protein (Accession Number: NM_198793). Purification method: Protein A purified.
  • Clonality
    Monoclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:1000-1:10000

  • Validations

    SKOV-3 cells were subjected to SDS PAGE followed by western blot with Catalog No:107138(CD47 Antibody) at dilution of 1:3000

    SKOV-3 cells were subjected to SDS PAGE followed by western blot with Catalog No:107138(CD47 Antibody) at dilution of 1:3000

  • Background
    CD47, also known as integrin-associated protein (IAP), is a member of the immunoglobulin superfamily containing a five-pass transmembrane attachment. CD47 is heavily glycosylated and widely expressed by hematopoietic and nonhematopoietic cells. CD47 interacts with several membrane integrins and also acts a receptor for thrombospondin (THBS1). It is involved in a range of cellular processes, including apoptosis, proliferation, adhesion, and migration. CD47 also functions as a ligand for signal regulatory protein-α (SIRPα). Upon binding CD47, SIRPα initiates a signaling cascade that results in the inhibition of phagocytosis.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"