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Product Name
CD336 antibody
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Description
CD336 Rabbit Polyclonal antibody. Positive WB detected in human spleen tissue. Observed molecular weight by Western-blot: 36-44kd
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Tested applications
ELISA, WB
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Species reactivity
human; other species not tested.
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Alternative names
NCR2 antibody; NK cell activating receptor antibody; NKP44 antibody; LymphOCyte antigen 95 homolog antibody; LY95 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_004828). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
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Validations
human spleen tissue were subjected to SDS PAGE followed by western blot with Catalog No:109029(CD336 antibody) at dilution of 1:500
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Background
CD336, also named as NCR2, LY95 and NKp44, belongs to the natural cytotoxicity receptor (NCR) family. It is cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. It is expressed on activated human NK cells. CD336 displays a single extracellular Ig-like V domain and a transmembrane portion containing the charged residue (Lysine), likely involved in the association with KARAP/DAP12 molecules. The antibody is specific to CD336.
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