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Product Name
CD300LF antibody
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Description
CD300LF Rabbit Polyclonal antibody. Positive IP detected in K-562 cells. Positive WB detected in K-562 cells, Jurkat cells, U-937 cells. Observed molecular weight by Western-blot: 30-34 kDa
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Tested applications
ELISA, WB, IP
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Species reactivity
Human; other species not tested.
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Alternative names
CD300f antibody; CD300LF antibody; CLM 1 antibody; CLM1 antibody; CMRF35 like molecule 1 antibody; IgSF13 antibody; IREM 1 antibody; IREM1 antibody; NK inhibitory receptor antibody; NKIR antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of CD300LF recombinant protein (Accession Number: NM_001289082). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IP: 1:500-1:5000
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Validations
K-562 cells were subjected to SDS PAGE followed by western blot with Catalog No:109023(CD300LF Antibody) at dilution of 1:1500
IP Result of anti-CD300LF (IP:Catalog No:109023, 4ug; Detection:Catalog No:109023 1:1500) with K-562 cells lysate 4000ug.
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Background
CD300LF, also known as CLM1 (CMRF35-like molecule 1), is a member of the CD300 protein family. Members of this family are cell surface glycoproteins with a single IgV-like extracellular domain, and are involved in the regulation of immune response. CD300LF is an inhibitory receptor that has been shown to inhibit various inflammatory processes in myeloid cells, such as macrophages and mast cells.
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References
- Grigoryev DN, Cheranova DI, Chaudhary S, Heruth DP, Zhang LQ, Ye SQ. Identification of new biomarkers for Acute Respiratory Distress Syndrome by expression-based genome-wide association study. BMC pulmonary medicine. 15:95. 2015.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"