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Product Name
CD2 antibody
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Description
CD2 Mouse Monoclonal antibody. Positive WB detected in Jurkat cells, Raji cells. Observed molecular weight by Western-blot: 45~55 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human; other species not tested.
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Alternative names
CD2 antibody; CD2 molecule antibody; ErythrOCyte receptor antibody; FLJ46032 antibody; LFA 2 antibody; LFA 3 receptor antibody; Rosette receptor antibody; SRBC antibody; T cell surface antigen CD2 antibody; T11 antibody
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Isotype
Mouse IgG1
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Preparation
This antibody was obtained by immunization of CD2 recombinant protein (Accession Number: NM_001767). Purification method: Caprylic acid/ammonium sulfate precipitation.
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Clonality
Monoclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:1000
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Validations
Jurkat cells were subjected to SDS PAGE followed by western blot with Catalog No:107049(CD2 antibody) at dilution of 1:400
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Background
CD2 is a cell surface glycoprotein present on a majority of thymocytes, all mature T cells and subset of NK cells but not on B lymphocytes. It is a pan T-cell marker. CD2 interacts with lymphocyte function-associated antigen (LFA-3/CD58) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"