CD109 antibody

CD109 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

CD109 Rabbit Polyclonal antibody. Positive WB detected in PC-3 cells. Positive IP detected in PC-3 cells. Observed molecular weight by Western-blot: 180 kDa,150 kDa,120 kDa,75 kDa

ELISA, WB, IP

Human; other species not tested.

CD109 antibody; CD109 antigen antibody; CD109 molecule antibody; CPAMD7 antibody; DKFZp762L1111 antibody; FLJ38569 antibody; FLJ41966 antibody; p180 antibody; Platelet specific Gov antigen antibody; r150 antibody; RP11 525G3.1 antibody

Rabbit IgG

This antibody was obtained by immunization of Peptide (Accession Number: XM_005248659). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

CD109, also named as CPAMD7, is a member of the alpha2-macroglobulin/complement superfamily. It is a glycosylphosphatidylinositol (GPI)-linked cell surface glycoprotein of approximately 170kd which is found on the cell surface of platelets, activated T-cells, and endothelial cells. CD109 binds to and negatively regulates signaling of transforming growth factor beta (TGF-beta). CD109 has been identified as part of the TGF-beta receptor system in human keratinocytes. Up regulation of CD109 expression has been observed in several different types of tumor.CD109 is a glycosyl-phosphatidylinositol-anchored glycoprotein that is a member of the a2-macroglobulin/C3, C4, C5 family of thioester-containing proteins. There're 2 forms of 150 (p150) and 120 kDa (p120) exist due to proteolytic degradation from a 180 kDa form. The antibody can recognize all these 4 isoforms.