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Product Name
CCBE1 antibody
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Description
CCBE1 Rabbit Polyclonal antibody. Positive WB detected in Transfected HEK-293 cells.
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Tested applications
ELISA, WB
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Species reactivity
Human; other species not tested.
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Alternative names
CCBE1 antibody; FLJ30681 antibody; Full of fluid protein homolog antibody; KIAA1983 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of CCBE1 recombinant protein (Accession Number: BC046645). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
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Validations
Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:108955(CCBE1 Antibody) at dilution of 1:700
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Background
CCBE1 (collagen and calcium-binding EGF domain-containing protein 1) is a secreted protein that is indispensible for lymphangiogenesis during development. CCBE1 may be a guidance molecule that regulates lymphangioblast budding and possibly migration (PMID: 19287381). The gene of CCBE1 maps to 18q21.32 and encodes a protein of 44 kDa that contains an EGF-like domain and two collagen-like domains. Mutations in the CCBE1 gene cause Hennekam lymphangiectasia-lymphedema syndrome (PMID: 19935664).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"