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Product Name
CBX6 antibody
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Description
CBX6 Rabbit Polyclonal antibody. Positive WB detected in HepG2 cells. Positive IHC detected in human skin tissue. Observed molecular weight by Western-blot: 55-60 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human; other species not tested.
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Alternative names
CBX6 antibody; chromobox homolog 6 antibody; Chromobox protein homolog 6 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of CBX6 recombinant protein (Accession Number: NM_014292). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
HepG2 cells were subjected to SDS PAGE followed by western blot with Catalog No:108948(CBX6 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human skin slide using Catalog No:108948(CBX6 Antibody) at dilution of 1:50
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Background
The Chromobox domain (Cbx) gene family, consisting of Polycomb and Heterochromatin Protein 1 genes, involves in transcriptional repression, cell cycle regulation and chromatin remodeling [PMID: 17486619]. Cbx6, other named neuronal pentraxin receptor (NPR), first described as a putative integral membrane pentraxin that interacts with neuronal pentraxin 1 and 2, has also been classified as a Pc protein [PMID: 14647293]. NPR was determined to be a member of a distinct pentraxin protein subfamily, and found to form heteropentamer swithNP1 andNP2, followed by release from cell membranes [PMID: 10748068].
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"