Cathepsin D antibody

Cathepsin D antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Cathepsin D Rabbit Polyclonal antibody. Positive IHC detected in human breast cancer tissue, human brain tissue. Positive WB detected in human brain tissue, A431 cells, HepG2 cells. Observed molecular weight by Western-blot: 32kd

ELISA, WB, IHC

Human, Mouse; other species not tested.

Cathepsin D antibody; CLN10 antibody; CPSD antibody; CTSD antibody

Rabbit IgG

This antibody was obtained by immunization of Peptide (Accession Number: NM_001909). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

CTSD(Cathepsin D) is also named as CPSD,belongs to the peptidase A1 family.It is ubiquitously expressed and is involved in proteolytic degradation, cell invasion, and apoptosis. The prepro- CTSD isoform has a molecular mass of 52 kDa, the pro-CTSD 48 kDa and the mature CTSD 32 kDa(PMID:10917609). It is a lysosomal acid protease found in neutrophils and monocytes and involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.Defects in CTSD are the cause of neuronal ceroid lipofuscinosis type 10 (CLN10).