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Product Name
CASPR antibody
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Description
CASPR Rabbit Polyclonal antibody. Positive WB detected in mouse brain tissue. Positive IHC detected in human cerebellum tissue. Observed molecular weight by Western-blot: 180-190 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
CASPR antibody; Caspr1 antibody; CNTNAP antibody; CNTNAP1 antibody; contactin assOCiated protein 1 antibody; Neurexin 4 antibody; Neurexin IV antibody; NRXN4 antibody; P190 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_003632). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:108882(CASPR antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human cerebellum using Catalog No:108882(CASPR antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemical of paraffin-embedded human cerebellum using Catalog No:108882(CASPR antibody) at dilution of 1:50 (under 40x lens)
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Background
CNTNAP1, also named as CASPR, NRXN4, p190, Neurexin IV and Neurexin-4, belongs to the neurexin family. It plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. CNTNAP1 seems to demarcate the paranodal region of the axo-glial junction. In association with contactin, CNTNAP1 may have a role in the signaling between axons and myelinating glial cells. This antibody is specific to CNTNAP1.
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