Caspase 2/p18 antibody

Cat.#: 108874

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Product Information

  • Product Name
    Caspase 2/p18 antibody
  • Documents
  • Description
    Caspase 2/p18 Rabbit Polyclonal antibody. Positive WB detected in HEK-293 cells, Jurkat cells, mouse kidney tissue. Positive IF detected in HEK-293 cells. Observed molecular weight by Western-blot: 45 kDa,32 kDa
  • Tested applications
    ELISA, WB, IF
  • Species reactivity
    Human, Mouse; other species not tested.
  • Alternative names
    CASP 2 antibody; CASP2 antibody; Caspase 2 antibody; Caspase 2/p18 antibody; Caspase2 antibody; ICH 1L antibody; ICH 1L/1S antibody; ICH1 antibody; NEDD 2 antibody; NEDD2 antibody; Protease ICH 1 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of Caspase 2/p18 recombinant protein (Accession Number: NM_032982). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IF: 1:20-1:200

  • Validations

    HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:108874(Caspase 2 Antibody) at dilution of 1:600

    HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:108874(Caspase 2 Antibody) at dilution of 1:600

    Immunofluorescent analysis of (-20oc Ethanol) fixed HEK-293 cells using Catalog No:108874(Caspase 2 Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

    Immunofluorescent analysis of (-20oc Ethanol) fixed HEK-293 cells using Catalog No:108874(Caspase 2 Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

  • Background
    CASP2(Caspase-2) is also named as ICH1, NEDD2 and belongs to the peptidase C14A family.It is involved in the activation cascade of caspases responsible for apoptosis execution and might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.It has 2 isoforms produced by alternative splicing and can exists almost as a dimer in solution(PMID:15865942).

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"