CaMKII beta antibody

CaMKII beta antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

CaMKII beta Rabbit Polyclonal antibody. Positive WB detected in mouse brain tissue, human brain tissue, SH-SY5Y cells. Positive IP detected in mouse brain tissue. Positive IHC detected in human gliomas tissue, human brain tissue. Observed molecular weight by Western-blot: 50-70 kDa

ELISA, WB, IHC, IP

Human,Mouse,Rat; other species not tested.

CaM kinase II subunit beta antibody; CAM2 antibody; CaMK II subunit beta antibody; CAMK2 antibody; CAMK2B antibody; CAMKB antibody; CaMKII beta antibody

Rabbit IgG

This antibody was obtained by immunization of CaMKII beta recombinant protein (Accession Number: NM_172081). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

CAMK2B(Calcium/calmodulin-dependent protein kinase type II subunit beta ), also named as CAM2, CAMK2 and CAMKB, belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family and CaMK subfamily. It is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. CAMK2B is a member of the NMDAR signaling complex in excitatory synapses, it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity. It plays a distinct role in the induction of anergy in T lymphocytes, by differential regulation of IL10 and IL2 gene transcription suggesting MEF2A as a molecular target which can integrate different calcium signals(PMID:22578382). This protein has 8 isoforms produced by alternative splicing with the molecular weight between 50 kDa and 73 kDa.

• Busse K, Strotmann R, Strecker K. Adaptive gene regulation in the Striatum of RGS9-deficient mice. PloS one. 9(3):e92605. 2014.