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Product Name
Calpain 11 antibody
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Description
Calpain 11 Rabbit Polyclonal antibody. Positive WB detected in PC-3 cells. Observed molecular weight by Western-blot: 81kd
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Tested applications
ELISA, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
Calpain 11 antibody; calpain11 antibody; CANP 11 antibody; CAPN11 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Calpain 11 recombinant protein (Accession Number: BC033733). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
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Validations
PC-3 cells were subjected to SDS PAGE followed by western blot with Catalog No:108834(CAPN11 antibody) at dilution of 1:1000
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Background
Calpains are a superfamily of related proteins, some of which have been shown to function as intracellular calcium-dependent cysteine proteases. Calpains consist of a variable large (80 kDa) subunit and an invariant small (30 kDa) subunit. The expression of calpain11 during spermatogenesis and its localization is spermatozoa suggest that it is involved in regulating calcium-dependent signal transduction events during meiosis and sperm functional processes(PMID:16541461). And the 110 kDa band protein may be regarded as a complex.
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